Histostat

Dosage Form: FOR ANIMAL USE ONLY
Histostat®

50

Nitarsone

Type A Medicated Article

An aid in the prevention of blackhead in turkeys and chickens

Must be mixed thoroughly in feed before use

Active ingredient

Nitarsone (4-nitrophenylarsonic acid) ................................................... 50%

(equivalent to 226.8 grams nitarsone per pound of product) in a carrier suitable for incorporation in feed.

Dosages and directions

Turkeys

Mix in feed so that 2,000 lbs (909 kg) of complete ration contain 12 oz. (340.2 g) of Histostat 50 equivalent to 0.01875% nitarsone. Start Histostat 50 medication depending on such factors as record of blackhead occurrence on the farm or in the area; climate and weather; and soil or litter condition. Continue as long as prevention is desired.

Chickens

Mix in feed so that 2,000 lbs (909 kg) of complete ration contain 12 oz. (340.2 g) of Histostat 50 equivalent to 0.01875% nitarsone. Give continuously for at least 3 weeks during periods of stress. Long-term medication is not necessary for chickens because of their natural resistance except at times of undue stress. Reduced feed consumption, onset of production, and errors in management may produce stresses which lower the resistance of chickens to blackhead.

Mixing directions

To secure an even distribution, mix Histostat 50 with a small amount of feed ingredients, then add the remainder of the ingredients and mix thoroughly.

Precautions

Early medication is essential to prevent spread of the disease. Adequate drinking water must be provided near feeders at all times. The drug is not effective in preventing blackhead in birds infected more than 4 or 5 days. Symptoms of blackhead do not appear until 10 to 15 days after birds become infected.

Caution

Use as the sole source of arsenic.

Warning

Keep out of reach of children. Overdosage or lack of water may result in leg weakness or paralysis. Discontinue use 5 days before slaughtering for human consumption to allow for elimination of the drug from edible tissue. In mixing, avoid inhaling dust. Avoid contact of product with skin, eyes and clothing. Wash thoroughly after handling. Dangerous for ducks, geese and dogs.

Poison Arsenic Antidote

If swallowed, call a physician, poison control center, or hospital immediately. Induce vomiting by giving Ipecac Syrup as directed.

Restricted Drug (California) - Use only as directed. Not for human use.

Marketed by

Alpharma Inc.

Bridgewater, New Jersey 08807

Net wt 50 LB (22.68 kg)

Trademarks

registered

by Alpharma Inc.

560310 0908

PRINCIPAL DISPLAY PANEL- 50 LB BAG

Histostat®

50

ALPHARMA

Nitarsone

Type A Medicated Article

NADA 7-616, Approved by FDA

Net wt 50 LB (22.68 kg)

ALPHARMA®

Histostat®

50

Histostat  50 nitarsone  granule

Product Information Product Type OTC TYPE A MEDICATED ARTICLE ANIMAL DRUG NDC Product Code (Source) 46573-650 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Nitarsone (Nitarsone) Nitarsone 226.8 g  in 0.45 kg

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color WHITE (off-white to tan) Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 46573-650-00 22.68 kg In 1 BAG None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
NADA	NADA007616	01/01/2009

Labeler - Alpharma Inc. Animal Health (070954094)

Revised: 05/2009Alpharma Inc. Animal Health